The FDA pregnancy category C for Retin-A means that it is unknown if the medication is dangerous to a fetus or a nursing newborn.
This warning was included on the medication’s original label.
(The FDA’s A, B, C, D, and X pregnancy classifications were eliminated in 2015 in favor of medication information that the agency feels would be more useful to consumers and healthcare professionals.)
As in past labels, the current Retin-A labels state that tretinoin was demonstrated to be teratogenic and fetotoxic at high dosages in rats (caused birth defects and was toxic to fetuses).
No human research has revealed the same association, and not all results of rodent studies can be applied to human studies.
However, Dr. Hirsch advises against taking retinoid treatments if you’re attempting to get pregnant, already pregnant, or nursing.
The unpleasant first side effects have worn off if you’ve been using Retin-A for over a few months.
Many people feel redness, burning, stinging, and peeling/exfoliation after using Retin-A for the first time.
Retin-A should typically be used gradually, starting at the lowest dose—possibly every other day—and working up to a daily schedule and larger dosages.
If you’re using Retin-A, stay out of the sun! You become more vulnerable to sunburn.
Acne in youngsters as early as 7 years old is relatively uncommon because of the tendency toward earlier puberty.
A 2019 research published in The Journal of Clinical and Aesthetic Dermatology assessed the usage of tretinoin in children to determine its efficacy and safety.
729 youngsters with acne ages 9 to 17 were treated with 05% lotion.
When compared to children who used a placebo lotion, the children receiving tretinoin had much less acne after 12 weeks of regular treatment.
Children under the age of 13 had the most remarkable improvements, while general side effects such as dryness and scaling were modest to severe.
In order to cure infantile acne, several conventional treatments, such as tretinoin, are advised.
Due to the limited number of times these medications have been tested on children, prudence and common sense should be used.
Vitamin A is also included in the oral medication Accutane (isotretinoin), although at considerably higher concentrations.
Serious birth abnormalities, miscarriages, and other issues during pregnancy may result from it.
You must enroll in the iPledge program, along with your doctor and pharmacist, in order to obtain an Accutane prescription.
You must also sign documentation certifying that you are aware of the risks associated with the medication and the program’s criteria.
All women of reproductive age are required to have two negative pregnancy tests before acquiring an initial 30-day prescription.
They are also required to have a negative pregnancy test each month to receive prescription refills.
Even after stopping the medication for a month, you are unable to donate blood.
Common tretinoin side effects
Even while tretinoin topical creams are excellent in treating acne, acne scars, fine lines, wrinkles, and skin discolorations.
They still have the potential to have negative effects, just like any other medication.
The following are some of the most typical adverse effects of tretinoin:
- Crusty skin
- Dry skin
- Increased sensitivity to the sun
- Pain surrounding the treated areas
- Peeling or flaky skin
- Scaling of the skin
- Skin irritation
- Skin discoloration
- Stinging or burning
- Worsening of acne
Following therapy, many tretinoin adverse effects, including skin peeling, disappear in two to six weeks.
The medicine can start to cure acne, tighten neck skin, erase dark spots, and generally help the skin seem younger once it begins to encourage the synthesis of new collagen.
Since tretinoin takes time to take action, it may take three to six months for someone to notice a difference in their sunspots or fine lines.
Prior to using this medication
If you have an allergy to it, you should avoid using tretinoin topical. Without consulting a doctor, never provide tretinoin topical to a youngster.
Some tretinoin topical products cannot be used by anybody under the age of 18.
Inform your physician if you’ve ever had:
- Either eczema or intolerance to seafood (the gel may contain ingredients derived from fish).
- The safety of topical tretinoin for use during pregnancy is unknown. If you are pregnant, let your doctor know.
- Breastfeeding a baby while using this medication might not be safe. Ask your doctor if there are any hazards.